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11th Global Experts Meeting on Chemistry And Computational Catalysis

Singapore City, singapore

Sandhya Jain

Sandhya Jain

Parul University, India

Title: Synthesis and biological evaluation of a new substituted 4-Carboxy Benzamide derivative to provide new therapeutic strategy for diabetes mellitus.

Biography

Biography: Sandhya Jain

Abstract

Diabetes mellitus is a major affective disorder, common in the general population. Worldwide there is a renewed interest in the development of an effective medicine against the most dreaded diseases. Earlier known the class of Phenyl substituted carboxylic acids and Benzamide Derivatives are found to be good candidate for inhibitors of various PTPs, especially as PTP-1B. In the present study we propose to develop a new substituted 4-Carboxy Benzamide derivative, these can be prepared and can be checked for antidiabetic activity. The experimental work has been divided into two main parts: 1.Synthesis Work   2. Biological Studies, Therefore which prove the Inhibition of PTPase and Activation of insulin receptor and downstream functions could provide new therapeutic strategy for diabetes mellitus