Scientific Program

Conference Series Ltd invites all the participants across the globe to attend 12th Global Experts Meeting on Chemistry and Drug Design Seoul, South Korea.

Submit your Abstract
or e-mail to

chemistrycongress@asiameets.com
chemistrycongress@globalconferences.net
asiaevents@conferenceseries.com

Scientific Program Day 1

Day :

  • Modern Approach Towards Pharmaceutical Chemistry | Advanced Chemistry | Technical Aspects of Analytical Chemistry | Discovery and Design of Material chemistry | Emerging Trends in Computer-Aided Drug Design | Latest Discoveries in Green Chemistry | Technological advancement in Organic Synthesis
Location: D-Ballroom-1
Speaker

Chair

Karen Tarasenko

Chem Space, USA

Speaker

Co-Chair

Omid Akbarzadeh

University of Malaya | Malaysia

Session Introduction

Weerasak Songoen

Kasetsart University, Thailand

Title: Preliminary antibacterial activity from the stem extracts of Nauclea orientalis and Artocarpus lakoocha
Speaker
Biography:

Weerasak Songoen has completed his Masters of Degree in Chemistry from Kasetsart University, Thailand. He is currently is pursuing his PhD under Science
Achievement Scholarship of Thailand from the Thai Government.

Abstract:

The antibacterial activity screening test of the stem extracts of Nauclea orientalis and Artocarpus lakoocha was accomplished using agar well diffusion method. Dried stem of both medicinal plants was sequentially extracted by hexane, dichloromethane, ethyl acetate and methanol. Inhibition zone of the extracts against ten bacterial strains including of Grampositive: Bacillus megaterium, Staphylococcus aureus, Streptococcus agalactiae, Bacillus subtilis and Gram-negative: Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumonia, Vibrio parahaemolyticus, Salmonella spp., Enterobacter aerogenes wasevaluated at 10,000 ppm concentration. The results revealed that the ethyl acetate and methanol extracts of A. lakoocha showed the inhibition against Vibrio parahaemolyticus, Staphylococcus agalactiae, Escherichia coli and Bacillus subtilis. Furthermore, the dichloromethane extract of N. orientalis and A. lakoocha also exhibited the inhibition against Vibrio parahaemolyticus and Streptococcus agalactiae, respectively. This present study suggested that the stem extracts of A. lakoocha can be applied for developing potential drug candidates from the natural source.

 

Atcahree Ratwatthananon

Kasetsart University, Thailand

Title: Synthesis and acetylcholinesterase inhibitory activity of piperate ester
Speaker
Biography:

Atcharee Ratwatthananon has completed her MSc from Kasetsart University. She is currently pursuing her PhD in Organic Chemistry at Department of Chemistry,
Faculty of Science, Kasetsart University, Thailand.

Abstract:

Piperine is a major alkaloid component of Piper retrofractum fruits, has been reported as an acetylcholinesterase inhibitor.In this study, a series of piperate esters were evaluated the acetylcholinesterase inhibitory activity comparing with piperine using modified Ellman method. These compounds were designed and synthesized from piperine, isolated from P. Retrofractum, by hydrolysis into piperic acid followed esterification with various alcohols to produce the corresponding esters in low to high yields. The results found that menthyl piperate showed acetylcholinesterase inhibitory activity in higher than piperine and the other piperate esters.

 

Anchulee Pengsook

Kasetsart University , Thailand

Title: Synthesis and insecticidal activity of phenylpropanoids against Spodoptera litura
Biography:

Anchulee Pengsook is currently pursuing her PhD from Department of Chemistry, Faculty of Science, Kasetsart University, Thailand. She has completed her Graduation and Masters of degree from the Kasetsart University.

Abstract:

Phenylpropanoids are found in natural products consisting of C6-C3 carbon skeleton that illustrated a wide range of biological activities. In this research, phenylpropanoids were synthesized for searching novel eco-friendly insecticides and investigated the structure and insecticidal activity relationship. Synthetic phenylpropanoids, which have been achieved from commercially available benzaldehyde derivatives in three steps; Knovenagel condensation, esterification to methyl ester and reduction of ester group into alcohol, were tested for insecticidal activity against second instar larvae of Spodoptera litura using topical application. Almost all compounds exhibited more than 30% mortality after 24 hours post-treatment at a dose of 2.0 μg/larva. The results indicated that the substituent group on the aromatic ring and side chain moieties of phenylpropanoids affected to the insecticidal activity.

Anchulee Pengsook

Kasetsart University , Thailand

Title: Synthesis and insecticidal activity of phenylpropanoids against Spodoptera litura
Biography:

Anchulee Pengsook is currently pursuing her PhD from Department of Chemistry, Faculty of Science, Kasetsart University, Thailand. She has completed her Graduation and Masters of degree from the Kasetsart University.

Abstract:

Phenylpropanoids are found in natural products consisting of C6-C3 carbon skeleton that illustrated a wide range of biological activities. In this research, phenylpropanoids were synthesized for searching novel eco-friendly insecticides and investigated the structure and insecticidal activity relationship. Synthetic phenylpropanoids, which have been achieved from commercially available benzaldehyde derivatives in three steps; Knovenagel condensation, esterification to methyl ester and reduction of ester group into alcohol, were tested for insecticidal activity against second instar larvae of Spodoptera litura using topical application. Almost all compounds exhibited more than 30% mortality after 24 hours post-treatment at a dose of 2.0 μg/larva. The results indicated that the substituent group on the aromatic ring and side chain moieties of phenylpropanoids affected to the insecticidal activity.