Dr. Suzan A. Khayyat has completed her PhD in Organic Chemistry by Faculty of Education – Jeddah, Saudi Arabia. She has worked as associate professor of organic Chemistry at King Abdulaziz University, Jeddah in Saudi Arabia. She has published more than 30 papers in reputed journals and has been serving as a Vice dean of Faculty of Science and Arts in Rabigh at King Abdulaziz, Jeddah, Saudi Arabia.
Lavender oil, obtained from the flowers of Lavandula angustifolia (Family: Lamiaceae) by steam distillation, The major component of lavender oil is linalyl acetate was isolated and epoxidated thermally and photochemically using (mcpba, H2O2) respectively to produce mixture of 6,7-epoxy-3,7-dimethyl-1-octene-3-yl acetate (3) and 1,2-epoxy-3,7-dimethyl-6-octene-3-yl acetate (4) photochemicaly, While produced epoxide 4 only thermally . On the other hand, photooxygenation of 1 using different singlet oxygen sensitizers gave two hydroperoxide derivatives of 6-hydroperoxy-3, 7-dimethylocta-1,7-diene-3-yl acetate (5) and 7-hydroperoxy-3,7-dimethylocta1,5-diene-3-yl acetate (6) in the presence of tetraphenyl porphin (TPP), whereas gave hydroperoxide 6 only using hematoporphyrin (HP). Studies on the antifungal especially Penicillium italicum and Rhizopus stolonifer showed that linalyl acetate and its epoxides and hydroperoxides derivatives have good antibacterial action.
I did my Ph. D. (Organic Chemistry) at the Indian Institute of Technology, Kharagpur, India. I carried out my research work under the supervision of Dr. Jayanta Kumar Ray (Professor of Chemistry) at the Department of Chemistry, Indian Institute of Technology, Kharagpur, India. I carried out two research project. Seven papers have been published in international journals in my Ph.D period from IIT kharagpur and ten international journals have been published from my college affiliation as corresponding author. In addition, I guide three students as research supervisor.
Pyrrole fused heterocyclic and carbocyclic compound at 1,2 position have been effective today as it is the part structure of natural and unnatural compounds that exhibit a variety of biological and biomedical properties. The wide variety of pyrrole substrate isolated from natural sources exhibited remarkable biological properties such as hypolipidemic, antimicrobial, anti-inflammatory and antitumour activity. Therefore, the development of efficient synthetic path to nitrogen-containing molecules is of paramount importance. Keeping these points in mind and growing need of society for new organic molecules our research oriented to create new pyrrole fused molecule which has photophysical and biological activity. In recent communication, we have successfully investigated short synthetic route of N-substituted pyrrole derivatives and their application to the healthy CHO cell line and a cancerous GL261 cell line were well studied. In continuation of the pyrrole fused heterocycles and carbocycles compound synthesis; we focused on the synthesis of pyrrole fused heterocyclic system by using very short and simple methodology and apply it to biological system.